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avatar for David E. Nichols, PhD

David E. Nichols, PhD

Emeritus Professor of Pharmacology, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana

David E. Nichols, PhD, is currently an Adjunct Professor of Chemical Biology and Medicinal Chemistry at the University of North Carolina, Chapel Hill, Eshelman School of Pharmacy.  Previously, he held the Robert C. and Charlotte P. Anderson Distinguished Chair in Pharmacology, and, in addition, was a Distinguished Professor of Medicinal Chemistry and Molecular Pharmacology at the Purdue University College of Pharmacy, where he taught both professional undergraduate, and graduate classes. Dr. Nichols was also an Adjunct Professor of Pharmacology and Toxicology at the Indiana University School of Medicine and taught in the medical curriculum.

Dr. Nichols received his Bachelor of Science degree in chemistry from the University of Cincinnati in 1969 and his Doctorate of Philosophy in medicinal chemistry from the University of Iowa in 1973, after which he did postdoctoral work in pharmacology at the University of Iowa, College of Medicine. He joined Purdue University as an Assistant Professor in 1974, where he remained until his retirement from Purdue in June 2012. In 2004, Dr. Nichols was named the Irwin H. Page Lecturer by the International Society for Serotonin Research, and in 2006, he received the first Provost’s Outstanding Graduate Mentor award from Purdue University.

Dr. Nichols has published more than 300 scientific articles, most of which deal with the relationship between molecular structure and biological action. His two principal research areas focused on drugs that affect serotonin and dopamine transmission in the central nervous system. He was continuously funded by the National Institutes of Health for nearly three decades and served on numerous government review panels. Dr. Nichols was a leader in the development of dopamine D1 receptor-selective agonists and holds several US patents in that area.

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